Small molecules which mimic Fasudil treatment
Canned Analysis
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General Information
AccessionDCA00012890
TitleSmall molecules which mimic Fasudil treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Fasudil treatment in the Forebrain astrocytes - 6 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e734e467bea600fb96d4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3275
Cell TypeForebrain astrocytes - 6 Hours
Drug NameFasudil
Organismmouse
PubChem CID3547
SMILES IDC1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM634511, GSM634519, GSM634527, GSM634535
Perturbed SamplesGSM634512, GSM634520, GSM634528, GSM634536
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25829
Gene Expression Omnibus
Rho kinase inhibitor fasudil effect on forebrain astrocyte culture: time course
48
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