Small molecules which reverse Nickel chloride treatment
Canned Analysis
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General Information
AccessionDCA00012899
TitleSmall molecules which reverse Nickel chloride treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Nickel chloride treatment in the H4-II-E-C3 LIVER-derived cell line - 140 uM cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e764e467bea600fb96ea
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3279
Cell TypeH4-II-E-C3 LIVER-derived cell line - 140 uM
Drug NameNickel chloride
Organismrat
PubChem CID24385
SMILES IDCl[Ni]Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM782280, GSM782281, GSM782291, GSM782292, GSM782302, GSM782303, GSM782313, GSM782314
Perturbed SamplesGSM782283, GSM782294, GSM782305, GSM782316
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31503
Gene Expression Omnibus
Heavy metal effect on liver derived cell line H4-II-E-C3
56
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