Small molecules which mimic Cadmium dichloride treatment
Canned Analysis
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General Information
AccessionDCA00012902
TitleSmall molecules which mimic Cadmium dichloride treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cadmium dichloride treatment in the H4-II-E-C3 LIVER-derived cell line - 1.2 uM cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dcaae467bea600fb9234
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3281
Cell TypeH4-II-E-C3 LIVER-derived cell line - 1.2 uM
Drug NameCadmium dichloride
Organismrat
PubChem CID24947
SMILES IDCl[Cd]Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM782280, GSM782281, GSM782291, GSM782292, GSM782302, GSM782303, GSM782313, GSM782314
Perturbed SamplesGSM782290, GSM782301, GSM782312, GSM782323
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31503
Gene Expression Omnibus
Heavy metal effect on liver derived cell line H4-II-E-C3
56
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