Small molecules which mimic Metoprolol treatment
Canned Analysis
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General Information
AccessionDCA00012912
TitleSmall molecules which mimic Metoprolol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Metoprolol treatment in the colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dc87e467bea600fb9224
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3287
Cell Typecolon
Drug NameMetoprolol
DrugBank IDDB00264
Organismhuman
PubChem CID4171
SMILES IDCC(C)NCC(COC1=CC=C(C=C1)CCOC)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM282862, GSM282863, GSM282864, GSM282865, GSM282866, GSM282867
Perturbed SamplesGSM282946, GSM282947, GSM282948, GSM282949, GSM282950
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11223
Gene Expression Omnibus
Colon epithelial biopsies of ulcerative colitis patients
70
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