Small molecules which mimic Morphine treatment
Canned Analysis
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General Information
AccessionDCA00012916
TitleSmall molecules which mimic Morphine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Morphine treatment in the Striatum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dcb2e467bea600fb9238
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3288
Cell TypeStriatum
Drug NameMorphine
DrugBank IDDB00295
Organismhuman
PubChem CID5288826
SMILES IDCN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM187965, GSM187966, GSM187967
Perturbed SamplesGSM187968, GSM187969, GSM187970
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7762
Gene Expression Omnibus
Morphine effect on the striatum
49
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