Small molecules which reverse Morphine treatment
Canned Analysis
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General Information
AccessionDCA00012921
TitleSmall molecules which reverse Morphine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Morphine treatment in the Striatum - DBA/2J mice - Acute morphine treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d464e467bea600fb8e86
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3488
Cell TypeStriatum - DBA/2J mice - Acute morphine treatment
Drug NameMorphine
DrugBank IDDB00295
Organismmouse
PubChem CID5288826
SMILES IDCN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM187983, GSM187984, GSM187985
Perturbed SamplesGSM187986, GSM187987, GSM187988
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7762
Gene Expression Omnibus
Morphine effect on the striatum
49
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