Small molecules which reverse Citalopram treatment
Canned Analysis
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General Information
AccessionDCA00012931
TitleSmall molecules which reverse Citalopram treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Citalopram treatment in the lymphoblastoid cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d053e467bea600fb8cbe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3292
Cell Typelymphoblastoid cells
Drug NameCitalopram
DrugBank IDDB00215
Organismhuman
PubChem CID2771
SMILES IDCN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM162898, GSM162900, GSM162903
Perturbed SamplesGSM162897, GSM162899, GSM162901
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7036
Gene Expression Omnibus
Lymphoblastoid cell lines from monozygotic twin pairs discordant for bipolar disorder
12
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