Small molecules which reverse Carbidopa treatment
Canned Analysis
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General Information
AccessionDCA00012933
TitleSmall molecules which reverse Carbidopa treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Carbidopa treatment in the jeujunum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dac8e467bea600fb915e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3293
Cell Typejeujunum
Drug NameCarbidopa
DrugBank IDDB00190
Organismmouse
SMILES IDNN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C.O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1144771, GSM1144772, GSM1144773, GSM1144777, GSM1144778, GSM1144779
Perturbed SamplesGSM1144768, GSM1144769, GSM1144770, GSM1144774, GSM1144775, GSM1144776
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE47099
Gene Expression Omnibus
Cholestatic intestinal injury model: jejunum
7
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