Small molecules which mimic Abiraterone treatment
Canned Analysis
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General Information
AccessionDCA00012938
TitleSmall molecules which mimic Abiraterone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Abiraterone treatment in the No Data cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d198e467bea600fb8d4c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgswaminath
CREEDS IDdrug:3300
Cell TypeNo Data
Drug NameAbiraterone
DrugBank IDDB05812
Organismhuman
SMILES IDO[C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]2([C@H]3CC=C2c2cccnc2)C)C1)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1195853, GSM1195856, GSM1195857, GSM1195862, GSM1195865
Perturbed SamplesGSM1195851, GSM1195852, GSM1195854, GSM1195855, GSM1195858, GSM1195859, GSM1195860, GSM1195861, GSM1195863, GSM1195864, GSM1195866, GSM1195867
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE49244
Gene Expression Omnibus
Abiraterone acetate and di-n-butyl phthalate (DBP) response in a human fetal testis xenograft bioassay
7
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