Small molecules which mimic Morphine treatment
Canned Analysis
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General Information
AccessionDCA00012942
TitleSmall molecules which mimic Morphine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Morphine treatment in the No Data cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d17de467bea600fb8d40
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgswaminath
CREEDS IDdrug:3304
Cell TypeNo Data
Drug NameMorphine
DrugBank IDDB00295
Organismmouse
PubChem CID5288826
SMILES IDCN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1217777, GSM1217782, GSM1217785
Perturbed SamplesGSM1217776, GSM1217778, GSM1217779, GSM1217780, GSM1217781, GSM1217783, GSM1217784, GSM1217786, GSM1217787, GSM1217788, GSM1217789, GSM1217790
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50382
Gene Expression Omnibus
Neonatal stress and morphine effects on right hippocampus
7
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