Small molecules which mimic Trichloroethylene treatment
Canned Analysis
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General Information
AccessionDCA00012956
TitleSmall molecules which mimic Trichloroethylene treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Trichloroethylene treatment in the Liver ( B6C3F1/J strain) - 24 hours after treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e646e467bea600fb966c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3312
Cell TypeLiver ( B6C3F1/J strain) - 24 hours after treatment
Drug NameTrichloroethylene
Organismmouse
PubChem CID6575
SMILES IDC(=C(Cl)Cl)Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM597080, GSM597098, GSM597117
Perturbed SamplesGSM597132, GSM597147, GSM597160
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24278
Gene Expression Omnibus
Interstrain differences in the liver effects of trichloroethylene
98
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