Small molecules which mimic Sodium arsenite treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012986
TitleSmall molecules which mimic Sodium arsenite treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Sodium arsenite treatment in the LUNGS of C57BL/6 males (on AIN-76A Diet) - Injection 1mg/kg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dcc5e467bea600fb9240
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3354
Cell TypeLUNGS of C57BL/6 males (on AIN-76A Diet) - Injection 1mg/kg
Drug NameSodium arsenite
Organismmouse
PubChem CID443495
SMILES ID[O-][As]=O.[Na+]
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM279232, GSM279235, GSM279264, GSM279270, GSM279275
Perturbed SamplesGSM279240, GSM279245, GSM279248, GSM279250, GSM279253
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11056
Gene Expression Omnibus
Lung response to chronic and acute exposure to ingested arsenic
56
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.