Small molecules which reverse Sodium arsenite treatment
Canned Analysis
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General Information
AccessionDCA00012993
TitleSmall molecules which reverse Sodium arsenite treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Sodium arsenite treatment in the LUNGS of C57BL/6 males (on AIN-76A Diet) - Added to food - 10ppb cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d084e467bea600fb8cd6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3357
Cell TypeLUNGS of C57BL/6 males (on AIN-76A Diet) - Added to food - 10ppb
Drug NameSodium arsenite
Organismmouse
PubChem CID443495
SMILES ID[O-][As]=O.[Na+]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM279232, GSM279235, GSM279264, GSM279270, GSM279275
Perturbed SamplesGSM279230, GSM279249, GSM279258, GSM279265, GSM279273
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE11056
Gene Expression Omnibus
Lung response to chronic and acute exposure to ingested arsenic
56
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