Small molecules which reverse Hypochlorous acid treatment
Canned Analysis
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General Information
AccessionDCA00013023
TitleSmall molecules which reverse Hypochlorous acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Hypochlorous acid treatment in the RAW 264.7 macrophage cell line - 0.7 mM cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1df33e467bea600fb9352
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3382
Cell TypeRAW 264.7 macrophage cell line - 0.7 mM
Drug NameHypochlorous acid
Organismmouse
PubChem CID24341
SMILES IDOCl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM387601, GSM387602, GSM387605, GSM387606
Perturbed SamplesGSM387677, GSM387678, GSM387679
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15457
Gene Expression Omnibus
Hypochlorous acid effect on macrophage cell line: dose response
49
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