Small molecules which reverse Vancomycin treatment
Canned Analysis
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General Information
AccessionDCA00013051
TitleSmall molecules which reverse Vancomycin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Vancomycin treatment in the Kidney (of BALB/c females) - Intravenous - 200mg/kg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e0cce467bea600fb9406
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3396
Cell TypeKidney (of BALB/c females) - Intravenous - 200mg/kg
Drug NameVancomycin
DrugBank IDDB14969
Organismmouse
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM189045, GSM189047, GSM189048, GSM189049, GSM189050, GSM189051
Perturbed SamplesGSM189058, GSM189059, GSM189060, GSM189062, GSM189063, GSM189064
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7793
Gene Expression Omnibus
Vancomycin effect on the kidney: dose response
42
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