Small molecules which mimic Androstanolone treatment
Canned Analysis
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General Information
AccessionDCA00013072
TitleSmall molecules which mimic Androstanolone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Androstanolone treatment in the LNCaP prostate cancer cells - 16 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e2b3e467bea600fb94dc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3411
Cell TypeLNCaP prostate cancer cells - 16 Hours
Drug NameAndrostanolone
Organismhuman
PubChem CID10635
SMILES IDCC12CCC(=O)CC1CCC3C2CCC4(C3CCC4O)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM190812, GSM190815, GSM190818
Perturbed SamplesGSM190814, GSM190817, GSM190820
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7868
Gene Expression Omnibus
Prostate cancer cell line response to dihydrotestosterone: time course
14
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