Small molecules which mimic Curcumin treatment
Canned Analysis
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General Information
AccessionDCA00013082
TitleSmall molecules which mimic Curcumin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Curcumin treatment in the HL-60 leukemia cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d9fee467bea600fb9104
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3425
Cell TypeHL-60 leukemia cells
Drug NameCurcumin
Organismhuman
PubChem CID969516
SMILES IDCOC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM405501, GSM405502
Perturbed SamplesGSM405497, GSM405498
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16160
Gene Expression Omnibus
Expression data of HL-60 leukemia cells after treatment with Curcumin and TCDD
14
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