Small molecules which reverse Quercetin treatment
Canned Analysis
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General Information
AccessionDCA00013091
TitleSmall molecules which reverse Quercetin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Quercetin treatment in the jejunum (wild type) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e0f9e467bea600fb941a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3429
Cell Typejejunum (wild type)
Drug NameQuercetin
DrugBank IDDB04216
Organismmouse
SMILES IDOc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM96873, GSM96874, GSM96875
Perturbed SamplesGSM96876, GSM96877, GSM96878
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4262
Gene Expression Omnibus
Quercetin effect on hepatic cytochrome P-450 oxidoreductase null mutants
84
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