Small molecules which mimic Quercetin treatment
Canned Analysis
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General Information
AccessionDCA00013094
TitleSmall molecules which mimic Quercetin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Quercetin treatment in the colon (POR null) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1deb9e467bea600fb931c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3431
Cell Typecolon (POR null)
Drug NameQuercetin
DrugBank IDDB04216
Organismmouse
SMILES IDOc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM96787, GSM96788, GSM96789
Perturbed SamplesGSM96790, GSM96791, GSM96792
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4262
Gene Expression Omnibus
Quercetin effect on hepatic cytochrome P-450 oxidoreductase null mutants
84
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