Small molecules which reverse Quercetin treatment
Canned Analysis
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General Information
AccessionDCA00013103
TitleSmall molecules which reverse Quercetin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Quercetin treatment in the liver (Western diet) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dee0e467bea600fb932e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3435
Cell Typeliver (Western diet)
Drug NameQuercetin
DrugBank IDDB04216
Organismmouse
SMILES IDOc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM935760, GSM935761, GSM935762, GSM935763, GSM935764, GSM935765
Perturbed SamplesGSM935766, GSM935767, GSM935768, GSM935769, GSM935770, GSM935771
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38141
Gene Expression Omnibus
Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice
7
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