Small molecules which reverse Curcumin treatment
Canned Analysis
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General Information
AccessionDCA00013115
TitleSmall molecules which reverse Curcumin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Curcumin treatment in the BV-2 microglial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ee87e467bea600fb9a10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3442
Cell TypeBV-2 microglial cells
Drug NameCurcumin
Organismmouse
PubChem CID969516
SMILES IDCOC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM579953, GSM579957, GSM579961
Perturbed SamplesGSM579954, GSM579958, GSM579962
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23639
Gene Expression Omnibus
Transcriptomic definition of curcumin treated microglia
7
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