Small molecules which reverse Coenzyme q10 treatment
Canned Analysis
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General Information
AccessionDCA00013131
TitleSmall molecules which reverse Coenzyme q10 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Coenzyme q10 treatment in the brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dd99e467bea600fb929e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3452
Cell Typebrain
Drug NameCoenzyme q10
Organismmouse
PubChem CID5281915
SMILES IDCC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM378042, GSM378043, GSM378044
Perturbed SamplesGSM378045, GSM378046, GSM378047
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE15129
Gene Expression Omnibus
Coenzyme Q10-dependent gene expression in SAMP1 mice tissues
105
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