Small molecules which reverse Vitamin e treatment
Canned Analysis
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General Information
AccessionDCA00013177
TitleSmall molecules which reverse Vitamin e treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Vitamin e treatment in the Brains of aged (30-month-old) B6C3F1 animals fed a diet containing alpha-tocopherol cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e808e467bea600fb9732
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3477
Cell TypeBrains of aged (30-month-old) B6C3F1 animals fed a diet containing alpha-tocopherol
Drug NameVitamin e
DrugBank IDDB00163
Organismmouse
PubChem CID14985
SMILES IDCC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM201796, GSM201797, GSM201799, GSM201801, GSM201802
Perturbed SamplesGSM201804, GSM201805, GSM201806, GSM201808, GSM201809
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8150
Gene Expression Omnibus
Vitamin E supplementation effect on aged brain
7
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