Small molecules which reverse Lipopolysaccharide treatment
Canned Analysis
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General Information
AccessionDCA00013189
TitleSmall molecules which reverse Lipopolysaccharide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Lipopolysaccharide treatment in the Peripheral blood-derived MONOCYTES - 2 hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d45be467bea600fb8e82
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3483
Cell TypePeripheral blood-derived MONOCYTES - 2 hours
Drug NameLipopolysaccharide
Organismhuman
PubChem CID11970143
SMILES IDCCCCCCCCCCCCCCCC1C(OC(C(C1OC(=O)CC(CCCCCCCCCCC)O)O)COC2C(C(C(C(O2)COC3(CC(C(C(O3)C(CO)O)OC4C(C(C(C(O4)C(CO)O)OP(=O)(O)OP(=O)(O)OCCN)OC5C(C(C(C(O5)C(COC6C(C(C(CO6)(C(CO)O)O)O)O)O)OP(=O)(O)O)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)OC9C(C(C(C(O9)CO)O)O)OC1C(
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM126988, GSM126993
Perturbed SamplesGSM126994, GSM126995
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5504
Gene Expression Omnibus
Peripheral blood-derived monocytes response to lipopolysaccharide: time course
28
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