Small molecules which reverse Resveratrol treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013211
TitleSmall molecules which reverse Resveratrol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Resveratrol treatment in the MCF7 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ddcde467bea600fb92b6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3501
Cell TypeMCF7 cells
Drug NameResveratrol
DrugBank IDDB02709
Organismhuman
SMILES IDOc1ccc(cc1)/C=C/c1cc(O)cc(c1)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM624008, GSM624009, GSM624010
Perturbed SamplesGSM624014, GSM624015, GSM624016
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE25412
Gene Expression Omnibus
Resveratrol induces downregulation of DNA repair genes in MCF7 human breast cancer cells.
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.