Small molecules which reverse Laminin treatment
Canned Analysis
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General Information
AccessionDCA00013213
TitleSmall molecules which reverse Laminin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Laminin treatment in the CD133+ and CD133- cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e7ffe467bea600fb972e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3502
Cell TypeCD133+ and CD133- cells
Drug NameLaminin
Organismhuman
PubChem CID44342165
SMILES IDCCC(C)C(C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)N
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM609023, GSM609025, GSM609027, GSM609029
Perturbed SamplesGSM609024, GSM609026, GSM609028, GSM609030
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24716
Gene Expression Omnibus
Expression data from CD133+ and CD133- glioma cells
7
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