Small molecules which mimic Resveratrol treatment
Canned Analysis
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General Information
AccessionDCA00013216
TitleSmall molecules which mimic Resveratrol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Resveratrol treatment in the gastrocnemius muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d375e467bea600fb8e1c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3504
Cell Typegastrocnemius muscle
Drug NameResveratrol
DrugBank IDDB02709
Organismmouse
SMILES IDOc1ccc(cc1)/C=C/c1cc(O)cc(c1)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM284992, GSM284993, GSM284994, GSM284995, GSM284996
Perturbed SamplesGSM285002, GSM285003, GSM285004, GSM285005, GSM285006
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11291
Gene Expression Omnibus
Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle
21
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