Small molecules which reverse Resveratrol treatment
Canned Analysis
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General Information
AccessionDCA00013217
TitleSmall molecules which reverse Resveratrol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Resveratrol treatment in the gastrocnemius muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d378e467bea600fb8e1e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3504
Cell Typegastrocnemius muscle
Drug NameResveratrol
DrugBank IDDB02709
Organismmouse
SMILES IDOc1ccc(cc1)/C=C/c1cc(O)cc(c1)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM284992, GSM284993, GSM284994, GSM284995, GSM284996
Perturbed SamplesGSM285002, GSM285003, GSM285004, GSM285005, GSM285006
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE11291
Gene Expression Omnibus
Effect of age, calorie restriction and resveratrol on gene expression in mouse heart, brain, and skeletal muscle
21
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