Small molecules which mimic Vitamin c treatment
Canned Analysis
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General Information
AccessionDCA00013220
TitleSmall molecules which mimic Vitamin c treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Vitamin c treatment in the Oct4-GiP mouse embryonic stem (ES) cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1de5be467bea600fb92f4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3506
Cell TypeOct4-GiP mouse embryonic stem (ES) cells
Drug NameVitamin c
DrugBank IDDB00126
Organismmouse
SMILES IDOC[C@@H]([C@H]1OC(=O)C(=C1O)O)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1128601, GSM1128602, GSM1128603
Perturbed SamplesGSM1128604, GSM1128605, GSM1128606
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46319
Gene Expression Omnibus
Vitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [Affymetrix]
7
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