Small molecules which reverse Vitamin c treatment
Canned Analysis
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General Information
AccessionDCA00013233
TitleSmall molecules which reverse Vitamin c treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Vitamin c treatment in the mouse embryonic fibroblast cells (MEF cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dc0ae467bea600fb91ee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3512
Cell Typemouse embryonic fibroblast cells (MEF cells)
Drug NameVitamin c
DrugBank IDDB00126
Organismmouse
SMILES IDOC[C@@H]([C@H]1OC(=O)C(=C1O)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM480923, GSM480924, GSM480925, GSM480926, GSM480927, GSM480928
Perturbed SamplesGSM480929, GSM480930, GSM480931, GSM480932, GSM480933, GSM480934
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19379
Gene Expression Omnibus
DNA microarrays time course of SKO-infected MEFs and MaF pre-iPSCs treated with Vc
14
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