Small molecules which reverse Vitamin c treatment
Canned Analysis
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General Information
AccessionDCA00013235
TitleSmall molecules which reverse Vitamin c treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Vitamin c treatment in the MaF pre-induced pluripotent stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1da0ae467bea600fb910a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3513
Cell TypeMaF pre-induced pluripotent stem cells
Drug NameVitamin c
DrugBank IDDB00126
Organismmouse
SMILES IDOC[C@@H]([C@H]1OC(=O)C(=C1O)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM480935, GSM480936, GSM480937, GSM480938
Perturbed SamplesGSM480939, GSM480940, GSM480941, GSM480942
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19379
Gene Expression Omnibus
DNA microarrays time course of SKO-infected MEFs and MaF pre-iPSCs treated with Vc
14
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