Small molecules which mimic Vitamin e treatment
Canned Analysis
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General Information
AccessionDCA00013236
TitleSmall molecules which mimic Vitamin e treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Vitamin e treatment in the aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d0c3e467bea600fb8cf0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3515
Cell Typeaorta
Drug NameVitamin e
DrugBank IDDB00163
Organismmouse
PubChem CID14985
SMILES IDCC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM478610, GSM478611
Perturbed SamplesGSM1050380, GSM1050381
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42813
Gene Expression Omnibus
Microarray gene expression profiling of aortic genes of APOE-deficient mice receiving atherosclerosis treatment with the antioxidant vitamin E
7
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