Small molecules which reverse Vitamin e treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013237
TitleSmall molecules which reverse Vitamin e treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Vitamin e treatment in the aorta cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d0c5e467bea600fb8cf2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3515
Cell Typeaorta
Drug NameVitamin e
DrugBank IDDB00163
Organismmouse
PubChem CID14985
SMILES IDCC1=C(C(=C2CCC(OC2=C1C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM478610, GSM478611
Perturbed SamplesGSM1050380, GSM1050381
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42813
Gene Expression Omnibus
Microarray gene expression profiling of aortic genes of APOE-deficient mice receiving atherosclerosis treatment with the antioxidant vitamin E
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.