Small molecules which mimic Dmnq (2,3-dimethoxy-1,4-naphthoquinone) treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013256
TitleSmall molecules which mimic Dmnq (2,3-dimethoxy-1,4-naphthoquinone) treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Dmnq (2,3-dimethoxy-1,4-naphthoquinone) treatment in the HepG2 - liver carcinoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d9ace467bea600fb90e0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3527
Cell TypeHepG2 - liver carcinoma cells
Drug NameDmnq (2,3-dimethoxy-1,4-naphthoquinone)
Organismhuman
PubChem CID3136
SMILES IDCOC1=C(C(=O)C2=CC=CC=C2C1=O)OC
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM159303, GSM159305, GSM159306
Perturbed SamplesGSM159336, GSM159337, GSM159338
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6907
Gene Expression Omnibus
Heavy metals effect on liver cell line
56
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.