Small molecules which mimic Formaldehyde treatment
Canned Analysis
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General Information
AccessionDCA00013274
TitleSmall molecules which mimic Formaldehyde treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Formaldehyde treatment in the Nasal EPITHELIA exposed to 0.7ppm - Inhalation - 6 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ed58e467bea600fb998a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3536
Cell TypeNasal EPITHELIA exposed to 0.7ppm - Inhalation - 6 Hours
Drug NameFormaldehyde
Organismrat
PubChem CID712
SMILES IDC=O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM159785, GSM159786, GSM159787, GSM159788, GSM159789, GSM159796, GSM159797, GSM159798
Perturbed SamplesGSM159727, GSM159728, GSM159806, GSM159807
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7002
Gene Expression Omnibus
Formaldehyde effect on nasal epithelium: dose response and time course
119
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