Small molecules which mimic Mehp treatment
Canned Analysis
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General Information
AccessionDCA00013342
TitleSmall molecules which mimic Mehp treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Mehp treatment in the Testes (prepubertal) - 1 hour cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d918e467bea600fb90a0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3576
Cell TypeTestes (prepubertal) - 1 hour
Drug NameMehp
Organismrat
PubChem CID20393
SMILES IDCCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM100955, GSM100956, GSM100957
Perturbed SamplesGSM100969, GSM100970, GSM100971
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4514
Gene Expression Omnibus
Mono-(2-ethylhexyl) phthalate effect on prepubertal testes: time course
35
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