Small molecules which reverse Mehp treatment
Canned Analysis
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General Information
AccessionDCA00013347
TitleSmall molecules which reverse Mehp treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Mehp treatment in the Testes (prepubertal) - 3 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d95ae467bea600fb90be
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3578
Cell TypeTestes (prepubertal) - 3 Hours
Drug NameMehp
Organismrat
PubChem CID20393
SMILES IDCCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM100960, GSM100961, GSM100962
Perturbed SamplesGSM100976, GSM100977, GSM100978
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4514
Gene Expression Omnibus
Mono-(2-ethylhexyl) phthalate effect on prepubertal testes: time course
35
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