Small molecules which mimic Leptin treatment
Canned Analysis
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General Information
AccessionDCA00013372
TitleSmall molecules which mimic Leptin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Leptin treatment in the Gallbladders (from leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d173e467bea600fb8d3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3592
Cell TypeGallbladders (from leptin-deficient obese females following daily treatment with 5 ug/g recombinant leptin for 4 weeks)
Drug NameLeptin
DrugBank IDDB05098
Organismmouse
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM74081, GSM74083, GSM74171, GSM74189
Perturbed SamplesGSM74190, GSM74191, GSM74192, GSM74194
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3293
Gene Expression Omnibus
Leptin effect on gallbladder
12
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