Small molecules which reverse Genistein treatment
Canned Analysis
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General Information
AccessionDCA00013397
TitleSmall molecules which reverse Genistein treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Genistein treatment in the Thymus (of ovariectomized C57BL/6) - 2 Days cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d38ae467bea600fb8e26
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3604
Cell TypeThymus (of ovariectomized C57BL/6) - 2 Days
Drug NameGenistein
Organismmouse
PubChem CID5280961
SMILES IDC1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM63205, GSM63206
Perturbed SamplesGSM63207, GSM63208
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2889
Gene Expression Omnibus
17beta-estradiol and genistein effect on thymus: time course
35
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