Small molecules which mimic Phosgene treatment
Canned Analysis
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General Information
AccessionDCA00013414
TitleSmall molecules which mimic Phosgene treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Phosgene treatment in the Lungs - 12 Hour after exposure cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d77fe467bea600fb8fe8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3614
Cell TypeLungs - 12 Hour after exposure
Drug NamePhosgene
Organismmouse
PubChem CID6371
SMILES IDC(=O)(Cl)Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM49354, GSM49355, GSM49356, GSM49357, GSM49360, GSM49361
Perturbed SamplesGSM49402, GSM49403, GSM49404, GSM49405, GSM49406, GSM49407
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE2565
Gene Expression Omnibus
Phosgene effect on lungs: time course
56
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