Small molecules which reverse Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00013425
TitleSmall molecules which reverse Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Estradiol treatment in the Uterus - - single injection of 400 ug/kg - 1 Hour after treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e22ce467bea600fb94a2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3619
Cell TypeUterus - - single injection of 400 ug/kg - 1 Hour after treatment
Drug NameEstradiol
DrugBank IDDB00783
Organismmouse
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM31735, GSM40014, GSM40028
Perturbed SamplesGSM31736, GSM40015, GSM40029
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2195
Gene Expression Omnibus
Uterus response to 17beta-estradiol: time course
49
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