Small molecules which mimic Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00013428
TitleSmall molecules which mimic Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Estradiol treatment in the Uterus - single injection of 400 ug/kg - 4 Hours after treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1de00e467bea600fb92cc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3621
Cell TypeUterus - single injection of 400 ug/kg - 4 Hours after treatment
Drug NameEstradiol
DrugBank IDDB00783
Organismmouse
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM31741, GSM40018, GSM40032
Perturbed SamplesGSM31742, GSM40019, GSM40033
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2195
Gene Expression Omnibus
Uterus response to 17beta-estradiol: time course
49
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