Small molecules which reverse Tretinoin treatment
Canned Analysis
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General Information
AccessionDCA00013451
TitleSmall molecules which reverse Tretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Tretinoin treatment in the cranial neural crest - 48 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d0bce467bea600fb8cee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3634
Cell Typecranial neural crest - 48 Hours
Drug NameTretinoin
DrugBank IDDB00755
Organismmouse
PubChem CID444795
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM27271, GSM27272, GSM27273, GSM27274
Perturbed SamplesGSM27275, GSM27276, GSM27277
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1588
Gene Expression Omnibus
Retinoic acid teratogenic effect on cranial neural crest: time course
28
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