Small molecules which mimic Halothane treatment
Canned Analysis
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General Information
AccessionDCA00013476
TitleSmall molecules which mimic Halothane treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Halothane treatment in the Whole brain - 5 exposures cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ebf5e467bea600fb98ea
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3651
Cell TypeWhole brain - 5 exposures
Drug NameHalothane
DrugBank IDDB01159
Organismrat
PubChem CID3562
SMILES IDC(C(F)(F)F)(Cl)Br
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM11379, GSM11380, GSM11381, GSM5082, GSM5084, GSM5085, GSM5086, GSM5087, GSM5090, GSM5105, GSM5106, GSM5107
Perturbed SamplesGSM5111, GSM5112, GSM5113
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6433
Gene Expression Omnibus
Anesthetic effect on brain
28
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