Small molecules which reverse Isoflurane treatment
Canned Analysis
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General Information
AccessionDCA00013483
TitleSmall molecules which reverse Isoflurane treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Isoflurane treatment in the Whole brain - 10 exposures cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e192e467bea600fb945e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3654
Cell TypeWhole brain - 10 exposures
Drug NameIsoflurane
DrugBank IDDB00753
Organismrat
PubChem CID3763
SMILES IDC(C(F)(F)F)(OC(F)F)Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM11379, GSM11380, GSM11381, GSM5082, GSM5084, GSM5085, GSM5086, GSM5087, GSM5090, GSM5105, GSM5106, GSM5107
Perturbed SamplesGSM5114, GSM5115, GSM5116
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6433
Gene Expression Omnibus
Anesthetic effect on brain
28
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