Small molecules which reverse Aldosterone treatment
Canned Analysis
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General Information
AccessionDCA00013485
TitleSmall molecules which reverse Aldosterone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Aldosterone treatment in the mIMCD-3 - inner medullary collecting duct cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1df99e467bea600fb937e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3655
Cell TypemIMCD-3 - inner medullary collecting duct cell line
Drug NameAldosterone
Organismmouse
PubChem CID5839
SMILES IDCC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C=O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM6603, GSM6605, GSM6607
Perturbed SamplesGSM6604, GSM6606
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE434
Gene Expression Omnibus
Aldosterone response
7
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