Small molecules which reverse Methylprednisolone treatment
Canned Analysis
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General Information
AccessionDCA00013491
TitleSmall molecules which reverse Methylprednisolone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Methylprednisolone treatment in the Skeletal muscle - 15 minutes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eacae467bea600fb9864
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3658
Cell TypeSkeletal muscle - 15 minutes
Drug NameMethylprednisolone
DrugBank IDDB00959
Organismrat
PubChem CID6741
SMILES IDCC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM5047, GSM5048, GSM5049, GSM5071
Perturbed SamplesGSM5075, GSM5076, GSM5077
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE490
Gene Expression Omnibus
Pharmacogenomic effect of corticosteroid in skeletal muscle
112
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