Small molecules which mimic Angiotensin ii treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013524
TitleSmall molecules which mimic Angiotensin ii treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Angiotensin ii treatment in the Aorta - 14 Days cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e38be467bea600fb953c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3679
Cell TypeAorta - 14 Days
Drug NameAngiotensin ii
Organismmouse
PubChem CID172198
SMILES IDCCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM447071, GSM447072, GSM447073, GSM447074, GSM447075, GSM447076
Perturbed SamplesGSM447089, GSM447090, GSM447091, GSM447092, GSM447093
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE17901
Gene Expression Omnibus
Abdominal Aortic Aneurysm in the ApoE Knockout Mouse: Time Course of Control vs. Angiotensin II
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.