Small molecules which reverse Capsaicin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00013541
TitleSmall molecules which reverse Capsaicin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Capsaicin treatment in the DRG neurons - 10 µM for 30 min cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ed04e467bea600fb9964
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3693
Cell TypeDRG neurons - 10 µM for 30 min
Drug NameCapsaicin
Organismrat
PubChem CID1548943
SMILES IDCC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1442972, GSM1442973, GSM1442974, GSM1442975
Perturbed SamplesGSM1442976, GSM1442977, GSM1442978, GSM1442979
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59727
Gene Expression Omnibus
The transcriptome of TRPV1-positive sensory neurons revealed by subgroup-elimination transcriptomics
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.