Enrichment analysis of genes dysregulated following Clozapine treatment
Canned Analysis
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General Information
AccessionDCA00013568
TitleEnrichment analysis of genes dysregulated following Clozapine treatment
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between Clozapine treated cells and untreated control cells in the brain, 4 week treatment cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3088526
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:2469
Cell Typebrain, 4 week treatment
Drug NameClozapine
DrugBank IDDB00363
Organismmouse
PubChem CID2818
SMILES IDCN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
Characteristic Direction parameters
Control SamplesGSM149811, GSM149812, GSM149813
Perturbed SamplesGSM149805, GSM149806, GSM149807
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE6511
Gene Expression Omnibus
Antipsychotic agents clozapine and haloperidol effects on the brain (I)
14
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